93 Results for "

Taxus cuspidata Siebold & Zucc.

" in MedChemExpress (MCE) Product Catalog:
Products (93)

93 Results for "Taxus cuspidata Siebold & Zucc." in MCE Product Catalog:

6
Toosendanin
Toosendanin
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6 Publications Verification
Cat. No.: HY-N0263
CAS No.: 58812-37-6
Category:  

Triterpenes Terpenoids Melia toosendan Sieb. et Zucc. Plants Disease Research Fields Inflammation/Immunology Meliaceae

Target:  

Others

Toosendanin, a triterpenoid extracted from the bark of fruit of Melia toosendan Sieb. et Zucc., possesses analgesic, insecticidal and anti-inflammatory activities .
6
Cornuside
Cornuside
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6 Publications Verification
Cat. No.: HY-N0631
CAS No.: 131189-57-6
Category:  

Cornaceae Iridoids Cornus officinalis Sieb. et Zucc. Terpenoids Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology

Target:  

p38 MAPK NF-κB JNK Cholinesterase (ChE) Acyltransferase NO Synthase Interleukin Related TNF Receptor Prostaglandin Receptor ERK COX

Cornuside is an iridoid glycoside with anti-allergic, anti-inflammatory, and neuroprotective activities. Cornuside exerts anti-allergic activity by downregulating the p38 MAPK, JNK, and NF-κB signaling pathways, and inhibits IgE-mediated histamine release from mast cells. Cornuside improves cognitive impairment in mice by inhibiting BACE1 activity (IC50 = 55.84 μg/mL) and enhancing ChAT activity. Cornuside inhibits LPS (HY-D1056)-induced inflammatory mediators, including iNOS, COX-2, PGE2, TNF-α, IL-6, and IL-1β, by suppressing NF-κB activation .
1
β,β-Dimethylacrylshikonin
β,β-Dimethylacrylshikonin
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1 Cited Publications
Cat. No.: HY-N5112B
CAS No.: 24502-79-2
Synonyms: Isoarnebin I
Category:  

Quinones Phenols Polyphenols Plants Lithospermum erythrorhizon Sieb. et Zucc. Disease Research Fields Boraginaceae Naphthalene Quinones Cancer

Target:  

HIF/HIF Prolyl-Hydroxylase Apoptosis Notch NO Synthase Bcl-2 Family

β,β-Dimethylacrylshikonin (Isoarnebin I) is a naphthoquinone derivative that can be isolated from Lithospermum erythrorhizon Sieb. et Zucc. β,β-Dimethylacrylshikonin promotes angiogenesis by inducing eNOS, VEGF and HIF-1α expression through the PI3K-dependent pathway. β,β-Dimethylacrylshikonin inhibits Notch-1 activation. β,β-Dimethylacrylshikonin inhibtis tumor cell proliferation, induces tumor cell apoptosis, and inhibits tumor growth .
1
Emodin-1-O-β-D-glucopyranoside
Emodin-1-O-β-D-glucopyranoside
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1 Cited Publications
Cat. No.: HY-N2394
CAS No.: 38840-23-2
Category:  

Quinones Rheum palmatum L. Polygonaceae Anthraquinones Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology

Target:  

Bacterial

Emodin-1-O-β-D-glucopyranoside, isolated from medicinal plant Polygonum cuspidatum Sieb. & Zucc, is a potent and noncompetitive bacterial neuraminidase (BNA) inhibitor with an IC50 of 0.85 μM .
10-Deacetylbaccatin III
10-Deacetylbaccatin III
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Cat. No.: HY-16565
CAS No.: 32981-86-5
Category:  

Terpenoids Taxaceae Diterpenoids Plants Disease Research Fields Cancer Taxus chinensis (Pilger) Rehd.

Target:  

Biochemical Assay Reagents Drug Intermediate Parasite

10-Deacetylbaccatin-III is an intermediate in the preparation process of paclitaxel. 10-Deacetylbaccatin III can be isolated from the dried needles and small branches of the European yew tree (Taxus baccata). 10-Deacetylbaccatin III exhibits antileishmanial activity .
(E/Z)-Polydatin
(E/Z)-Polydatin
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Cat. No.: HY-N0120
CAS No.: 65914-17-2
Synonyms: (E/Z)-Piceid
Category:  

Stilbenes Polygonaceae Reynoutria japonica Houtt. Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology

Target:  

Drug Isomer

(E/Z)-Polydatin ((E/Z)-Piceid) is a mixture of the E/Z configurations of Polydatin (HY-N0120A). Polydatin can be isolated from Polygonum cuspidatum, grapes, peanuts, red wine, hop pellets, cocoa-containing products and chocolate products. Polydatin exhibits multiple biological properties, such as anti-platelet aggregation, anti-low-density lipoprotein oxidation, cardioprotective activity, anti-inflammatory and immunomodulatory functions. Polydatin shows favorable cytotoxic effects against various tumor cell lines, including cervical cancer cells, liver cancer cells, and nasopharyngeal carcinoma cells .
10-Deacetyltaxol
10-Deacetyltaxol
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Cat. No.: HY-N1391
CAS No.: 78432-77-6
Synonyms: 10-Deacetylpaclitaxel
Category:  

Terpenoids Taxaceae Diterpenoids Plants Disease Research Fields Cancer Taxus wallichiana Zucc.

Target:  

Microtubule/Tubulin

10-Deacetyltaxol (10-Deacetylpaclitaxel) is a taxane derivative isolated from Taxus wallichiana Zucc . 10-Deacetyltaxol (10-Deacetylpaclitaxel) promotes the polymerization of tubulin and to inhibit the depolymerization of microtubules induced by cold or by calcium ions in vitro . 10-Deacetyltaxol (10-Deacetylpaclitaxel) exhibits cytotoxicity in human glial and neuroblastoma cell-lines .
Flutax-2 (5/6-mixture)
Flutax-2 (5/6-mixture)
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Cat. No.: HY-131010
Purity:  88.82%
Flutax-2 (5/6-mixture) is an active fluorescent derivative of paclitaxel. Flutax-2 (5/6-mixture) binds to a polymerized α,β tubulin dimer. Excitation/emission wavelength: 496/524 nm. Paclitaxel, a diterpenoid secondary metabolite produced by Taxus species, can be used for the research of a variety of cancers .
Vitisin A
Vitisin A
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Cat. No.: HY-142026
CAS No.: 142449-89-6
Synonyms: (+)-Vitisin A
Category:  

Vitis vinifera cv. Zalema Phenols Polyphenols Plants Vitaceae

Target:  

Caspase ERK NF-κB Influenza Virus PAK LDLR PPAR PCSK9 Androgen Receptor Keap1-Nrf2 Monoamine Oxidase Cholinesterase (ChE) IKK Wnt β-catenin Reactive Oxygen Species (ROS) Apoptosis Cuproptosis

Vitisin A ((+)-Vitisin A) is an orally active natural product with multiple pharmacological activities including anti-inflammatory, anti-tumor, anti-oxidant, anti-pathogenic microorganism, hypoglycemic and lipid-regulating, anti-osteoporotic, neuroprotective and cardiovascular protective effects. Vitisin A exhibits inhibitory effects on human AChE and MAO-B with IC50 values of 1.29 µM and 4.94 µM, respectively. Vitisin A inhibits the ERK, MAPK, NF-κB, STAT1, HMGCR and TRAF6 pathways, downregulates the related phosphorylation and protein expression, while activates the Nrf2/HO-1 pathway and upregulates p21 expression. Vitisin A induces tumor cell apoptosis and cell cycle arrest, inhibits adipogenesis and lipid accumulation, while alleviates oxidative stress, suppresses inflammatory responses, blocks hepatic fibrosis, Cuproptosis and cholesterol synthesis, and increases the expression levels of central BDNF and TrkB. Vitisin A can be used in the research of tumors, infectious diseases, metabolic diseases, bone and joint diseases, liver diseases, skin injuries, as well as neurodegenerative and cognitive dysfunction-related diseases .
Guaiacin
Guaiacin
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Cat. No.: HY-N2247
CAS No.: 36531-08-5
Category:  

Zingiber officinale Roscoe Lignans Metabolic Disease Phenols Polyphenols Phenylpropanoids Plants Disease Research Fields Zingiberaceae

Target:  

Phosphatase

Guaiacin is a arylnaphthalene type lignin isolated from the barks of Machilus thunbergii SIEB. et ZUCC (Lauraceae). Guaiacin significantly increases alkaline phosphatase activity and osteoblast differentiation .
Dihydrocephalomannine
Dihydrocephalomannine
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Cat. No.: HY-N7256
CAS No.: 159001-25-9
Category:  

Other Terpenoids Terpenoids Plants Cephalotaxaceae Disease Research Fields Cancer Cephalotaxus fortunei Hooker

Target:  

Microtubule/Tubulin

Dihydrocephalomannine (compound 1b), an analogue of Paclitaxel, shows reduced cytotoxicity and tubulin binding compared to Paclitaxel .
Taxezopidine G
Taxezopidine G
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Cat. No.: HY-N7348
CAS No.: 205440-22-8
Category:  

Taxus cuspidata Siebold & Zucc. Ketones, Aldehydes, Acids Taxaceae Plants

Target:  

Others

Taxezopidine G is a natural product, that can be isolated from the seeds and stems of Japanese Yew Taxus cuspidata .
7-xylosyltaxol
7-xylosyltaxol
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Cat. No.: HY-77574
CAS No.: 90332-66-4
Synonyms: 7-Xylosylpaclitaxel; Taxol-7-xyloside
Category:  

Terpenoids Taxaceae Diterpenoids Plants Disease Research Fields Cancer Taxus chinensis (Pilger) Rehd.

Target:  

Microtubule/Tubulin

7-Xylosyltaxol (Taxol-7-xyloside) is a derivative of Paclitaxel (HY-B0015) found in the bark of Taxus wallichiana var. mairei. 7-Xylosyltaxol inhibits the growth of various cancer cells. 7-Xylosyltaxol can be used in cancer-related research .
Taxinine M
Taxinine M
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Cat. No.: HY-133194
CAS No.: 135730-55-1
Category:  

Natural Products Taxus cuspidata Siebold & Zucc. Taxaceae Plants

Target:  

Others

Taxinine M, a tetracyclic taxane, can be isolated from Taxus brevifolia .
β-Sitosterol acetate, 95%
β-Sitosterol acetate, 95%
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Cat. No.: HY-W127616A
CAS No.: 915-05-9
Synonyms: Sitosteryl acetate, 95%
β-Sitosterol acetate, 95% (Sitosteryl acetate, 95%) is a sterol that can be isolated from Hechtia glomerata Zucc., which has antibacterial activity and has a MIC value of 100µg/mL against carbapenem-resistant Acinetobacter baumannii .
Taxinine B
Taxinine B
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Cat. No.: HY-N1171
CAS No.: 18457-44-8
Synonyms: Taxinin B
Category:  

Natural Products Taxus cuspidata Siebold & Zucc. Taxaceae Plants

Target:  

Microtubule/Tubulin

Taxinine B is a taxoid that can be isolated from Japanese Yew Taxus Cuspid. Taxinine B inhibits CaCl2-induced depolymerization of microtubule. Taxinine B is useful for overcoming multidrug resistance in tumor cells .
Taxuspine W
Taxuspine W
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Cat. No.: HY-N7294
CAS No.: 181309-92-2
Category:  

Taxus cuspidata Siebold & Zucc. Ketones, Aldehydes, Acids Taxaceae Plants

Target:  

Others

Taxuspine W is a natural product, that can be isolated from the Japanese Yew Taxus cuspidata .
7-Deacetoxytaxinine J
7-Deacetoxytaxinine J
0 Images
Cat. No.: HY-N7460
CAS No.: 18457-45-9
Category:  

Taxus cuspidata Siebold & Zucc. Terpenoids Taxaceae Diterpenoids Plants

Target:  

Others

7-Deacetoxytaxinine J is a Diterpenoids product that can be isolated from the heartwoods of Taxus cuspidata. .
2-Deacetoxy-taxinine J
2-Deacetoxy-taxinine J
0 Images
Cat. No.: HY-N7573
CAS No.: 119347-14-7
Category:  

Taxus cuspidata Siebold & Zucc. Terpenoids Taxaceae Diterpenoids Plants

Target:  

Others

2-Deacetoxy-taxinine J is a Diterpenoids product that can be isolated from the heartwoods of Taxus cuspidata. .
2,7-Dideacetoxytaxinine J
2,7-Dideacetoxytaxinine J
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Cat. No.: HY-N7734
CAS No.: 115810-14-5
Category:  

Taxus cuspidata Siebold & Zucc. Terpenoids Taxaceae Diterpenoids Plants

Target:  

Others

2,7-Dideacetoxytaxinine J is a Diterpenoids product that can be isolated from the heartwoods of Taxus cuspidata. .
Assay Types